Axolbio/axolGEM iPSC-Derived Neural Stem Cells MAPT P301L HOM/ax0324/1 Ea,Axolbio,,Axolbio,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Axolbio/axolGEM iPSC-Derived Neural Stem Cells MAPT P301L HOM/ax0324/1 Ea

产品编号：ax0324

市场价：¥25600.00

场地：美国(厂家直采)

产品分类：细胞相关>细胞株>常规细胞株>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$1280.00

品牌： Axolbio

公司：Axolbio

公司分类：

商品介绍

axolGEMiPSC-DerivedNeuralStemCellsMAPTP301LHOM(1.5millioncells)andNeuralPlating-XFMedium(30mL)

Description:

HumaniPSC-DerivedNeuralStemCellsthathavebeengeneticallyeditedusingCRISPR-Cas9technologytointroducetheP301Lmutation(CCG>CTG)intotheMAPTgene.ThislineishomozygousfortheP301Lmutationsobothallelescontainthemutation.Clickontheproductimagestoseethedataandfurtherdetails.

TheP301LmutationMAPThasbeenimplicatedinfrontotemporaldementiaandparkinsonism(Dumanchinetal.,1998).Themutationaffectsonlythe4RisoformsofMAPTsincetheexoncontainingthemutationissplicedoutof3Risoforms(Huttonetal.,1998).AggregatedMAPT/tauproteininaffectedpatientsconsistedmainlyofthe4Risoform(Huttonetal.,1998).TheP301LmutationpromotesaggregationofMAPT/tauproteinintoorderedpairedhelicalfilamentsandbetasheetformationinvitro(vonBergenetal.,2001).

ClickheretoseemoredataonAxolNeuralStemCells

ProductSpecification:

Startingmaterial	Dermalfibroblast
Donorgender	Female
Donorageatsampling	64yrs
Karyotype	Normal
Reprogrammingmethod	Episomalvector
Inductionmethod	Monolayer&chemicallydefinedmedium
Geneticmodification	HomozygousfortheMAPTP301Lmutation(CCG>CTG)
Geneticmodification	Containsapuromycinresistancecassette(intronic)
Size	≥1.5millioncells
Kitcomponents	1vialofNeuralStemCells(≥1.5millioncells)and1bottleofNeuralPlating-XFMedium(30mL)
Growthproperties	Adherent
Shippingconditions	Dryice
Storageconditions	Liquidnitrogen